Exascale Framework for Digital Twins of the Human Body
dealiiX is a pioneering project aimed at developing a scalable, high-performance computational platform using the deal.II library to create accurate digital twins of human organs.
Recent NEWS
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dealiiX Seminar Highlights: Modeling and Simulation of Surfactant Effects on Finely Resolved Alveolar Structures
Mechanical ventilation is essential for patients with impaired lung function, but it can also damage lung tissue. Understanding its effects at the level of the
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VPH Leads European Policy Initiative on AI and Virtual Human Twins
The VPH – The Society for In Silico Medicine, a partner in the dealiiX project, continues to play a leading role in shaping the future
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VPH Society Statement: In Silico Evidence in the Revised MDR
VPH Society Statement: In Silico Evidence in the Revised MDR VPH Society has submitted a statement to the European Parliament’s SANT Committee on the revised
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dealiiX Project Review: A Milestone Recognised by the European Commission
The dealiiX project has successfully passed its review meeting with the European Commission. Reviewers acknowledged the quality of the work carried out by all consortium
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dealiiX Seminar Highlights: Cellular Motility and Integrin Relocation: From Theory to HPC Simulations
How do cells move, sense their environment, and adapt their behaviour?This question sits at the heart of some of biology’s most consequential processes: tumour metastasis,
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dealiiX Seminar Highlights: Efficient Matrix-Free Finite Element Solvers with deal.II
Last week, the dealiiX seminar series hosted an insightful session titled “Efficient Finite Element solvers with the matrix-free infrastructure of deal.II”, delivered by Prof. Martin
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Use case
Simulation of airflow in the human lung
Simulation of airflow in the human lung coupled to gas exchange processes through fully resolved coupled Navier-Stokes / poromechanics models for capturing pathologies at full scale.

Use case
Digital Twin of the human liver
Development of a digital twin of the human liver through multiscale representations of the vascular structure by effective biomechanical properties to enable data-driven enhanced personalization.
Use case
Simulation of brain tissue mechanics
Simulation of brain tissue mechanics through refined nonlinear routines for inverse parameter identification and related problems in the study of physiological and pathological scenarios.
Use case
Simulation in cardiac computational medicine
Simulation in cardiac computational medicine by multiscale and multiphysics models with extreme spatial and temporal resolution to gain novel insights.

Lighthouse applications representing crucial processes in the human brain, the cardiovascular and respiratory systems as well as the liver will be tackled to gain new insights into biological processes of the human body and aiding in personalized medicine.
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